2024 Conference
27th European GERPAC Conference
October 2, 3 & 4, 2024 - Hyères - France
In this space, you will find all the congress communications including conferences, round table, short oral communications and poster presentations.
Opening of the conference
Opening of the conference
S. Crauste-Manciet (President of the GERPAC)
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Concurrent workshops
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Couldn’t attend all the workshops?Don’t worry: we’re offering you access to P. Sessink and B.Tans workshop.
Validation of aseptic pharmaceutical preparations
Prof. Irene Kramer-Mainz (DE)/ Dr Paul Le Brun, Leiden (NL)
EU Guidance for safe management of hazardous medicinal products at work
Dr Paul Sessink, exposure control, Bjökö - SwedenDr Birgit Tans, University Hospitals Leuven - Belgium
Practical stability studies in hospital pharmacies
Dr Philip Chennell, CHU Clermont-Ferrand - FranceDr Elise d’Huart, CHRU Nancy - France
Dr Camille Merienne, HCL, Lyon - France
Creating a Compounding Unit
Dr Laurence Escalup, Institut Curie, Paris - FranceDr Marie-Noëlle Guerrault-Moro, CHI Poissy-St Germain - France
Dr Isabelle Roland, CHU Liège - Belgique
Training in the management of cytotoxic breakage through simulation: a team challenge
Dr Alexandra Garnier (CH) University Hospital Geneva / Dr Lucie Bouchoud (CH) University Hospital Geneva
What is the future of hospital pharmaceutical technologies ?
Moderators
F Lagarce (Angers - France) - T Briot (Lyon - France) - F Marçon (Amiens - France)
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What is the future of hospital pharmaceutical technologies ?
Pr Pascal BonnabryHUG, Geneva - Switzerland
Biotherapies: role of the hospital pharmacist
Prof. Frederic Lagarce Angers University Hospital France
Hospital Pharmacist role - Risk analysis for new therapeutics production
Dr Frederic Marçon -Assistant Professor-CHU Amiens University Hospital- France
Manufacturing of new biotherapies risk analysis. Example of point of care manufacturing of CAR-T cells
Dr Chantal Le Chanteur, Liège University Hospital, Belgium
Phage therapy
Dr Thomas Briot Lyon University hospital, France
Autologous serum eye drops
Dr Lucie Bouchoud, Genève University Hospital, Switzerland
Special Practice feedbacks
Moderators
I Krämer (Mainz - Germany) - P Odou (Lille - France) - S Crauste-Manciet (Paris - France) - T Storme (Paris - France)
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Specific features of pharmaceutical technologies in French overseas territories
Dr Christophe Padoin, University Hospital of Martinique, France
Large scale compounding in a Norwegian hospital pharmacy
Randi Hamre Svendsen Sterile manufacturing unit Oslo Hospital Pharmacy - Norvège
Large scale production in The Netherlands
Dr Marleen Kemper, Apotheek A15, The Netherlands
Large scale aseptic hospital production in the UK
Dr Andy Lowey, Lead Clinician - Preparative Services, Leeds Teaching Hospitals NHS Trust, England, UKInteractive case study
Moderators
T Storme (Paris - France) - F Sadeghipour (Lausanne - Switzerland)
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Interactive case study
GERPAC award 2024 for the best oral communication
Pharmaceutical Technology Master award
Moderators
S Crauste-Manciet (Angers - France) - F Lagarce (Angers - France)
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Application of Raman spectroscopy for qualitative and quantitative analysis of three cephalosporin solutions through infusion containers
Manon Dayrea,b, Marion Bergea,a,b, Samuel Zaouia,a,b, Ali Tfaylib, Eric Caudrona,a,b, Laetitia Lea,a,ba Univ. Paris-Saclay, Lip(Sys)2 Chimie Analytique Pharmaceutique, EA7357, UFR-Pharmacy, Saclay, France
b European Georges Pompidou Hospital (AP-HP), Pharmacie à Usage Intérieur, Paris, France
Statistical process control (SPC): application to a cytotoxic reconstitution unit
F. Gaume a, L. Le Quaya, A. Lebretona, M. Delamottea, F. Lagarce a,ba Pharmacie Centrale, CHU d’Angers, 49933 Angers, France
b Inserm U1066, CNRS 6021, micro- et nanomédecines biomimétiques, université Bretagne-Loire, 49933
Angers, France
Design and characterization of 2% propofol lipid nanocapsules formulated by microfluidics
Emilie Tireau a,b, Marie Bonnin a, Jean-Christophe Gimel a, Louise Stinat a,b, Guillaume Lefebvre a, Nolwenn Lautram a, Frederic Lagarce a,b, Brice Calvignac a, Sylvie Crauste-Manciet a,ba Université d’Angers, CHU Angers, INSERM, CNRS, MINT, SFR ICAT, 49000 Angers, France
b CHU Angers, département Pharmacie, 4 rue Larrey, 49933 Angers cedex 9, France
Short oral communications
Moderators
F Sadeghipour (Lausanne - Switzerland) - Y Huon (Liège - Belgium) - P Chennel (Clermont Ferrand - France) - C Merienne (Lyon - France)
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Operational Qualification of a 3D Printer for Drug Manufacturing
C. Razeyre1, V. Delannoy1, I. Soulairol1,21 Pharmacie, Centre Hospitalier Universitaire de Nîmes, France
2 ICGM, Université de Montpellier, CNRS, ENSCM, Montpellier, France
3D printing as a way towards new galenic forms: formulation and control of gummies containing Amiodarone or Diazoxide
I. Killisly, A. Gillette, S. Crauste-Manciet, F. Lagarce, S. Vrignaud, V. LebretonService de Pharmacie, CHU d’Angers, France
Assessment of cross-contamination risk, between two products, in a robotized anticancer drugs compounding process (RIVA® ARxIUM)
M. Devries 1, C. Danel1,2, L. Negrier1,2, A. Lecoutre1, J. Courtin1, M. Vasseur1,2, P. Odou1,2, N. Simon1,21 CHU Lille, Institut de pharmacie, F-59000 Lille, France
2 Univ. Lille, CHU Lille, ULR 7365 - GRITA - Groupe de Recherches sur les formes Injectables et les Technologie Associées, F-59000 Lille, France
Development and validation of a production and a dosage methods of 3D printed tablets containing prednisolone
A. Pierrot1, L. Zucaro1, J. Pezzatti1, L. Carrez1, F. Sadeghipour1,2,31 Service de pharmacie, Centre Hospitalier Universitaire Vaudois, Lausanne
2 Section des Sciences Pharmaceutiques, Ecole de Pharmacie Genève-Lausanne, Université de Genève
3 Centre de recherche et d’innovation en sciences pharmaceutiques et cliniques, Université de Lausanne, Suisse
SmartCompounders Chemo® does it well perform? Statistical study and capability analysi
C. Dréano, M. Delamotte, A. Lebreton, S. Crauste-Manciet, F. LagarcePharmacy, CHU d’Angers, 4 rue Larrey, 49100 ANGERS, France
How about 3D films? 3D printing development and characterization of an orodispersible hydrocortisone film formulation
L. Demange - - Labriet, L. Denis, M. Annereau, C. Boisseillier, D. Kariyawasam, P. Marchadour, A-S. Fauqueur, A. Rieutord, C. Cotteret, S. Cisternino, A. Schweitzer-ChaputPharmacie à Usage Intérieur, APHP, Hôpital Necker Enfants Malades et Institut Gustave Roussy, Paris et Villejuif, France
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Preliminary palatability tests for the use of 3D printed gummies
I. Killisly, A. Gillette, N. Guillon, V. Lebreton, S. Vrignaud, F. Lagarce, S. Crauste-MancietService de Pharmacie, CHU d’Angers, France
Feedback from sixteen-month experience of using two robotic systems for sterile chemotherapy compounding in isolators and under laminar flow hoods in the same unit
J-S. Giraud, S. Busse, E. Kobylarz, A. Hammadi, F. Khodja, K. Lazaro, A. Acramel, A. Hurgon, R. Desmaris, C. CrosInstitut Curie, Paris, France
Assessment of chemical stability of monoclonal antibody and antibody drug conjugate administered by pressured intraperitoneal aerosol chemotherapy
G. Galy1, V. D’Atri2, M. Buff2, M. Imiolek3, M Hübner4, S. Intidhar Labidi-Galy5, D. Guillarme2, L. Carrez11 Service Pharmacie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse
2 Institut des Sciences Pharmaceutiques de Suisse occidentale, Université de Genève, CMU Genève, Suisse
3 Waters Corporation, Genève, Suisse
4 Service de chirurgie viscérale, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Université de Lausanne (UNIL)
5 Département d’oncologie, Hôpitaux Universitaires de Genève, Genève, Suisse
Physical stability of bevacizumab solutions for intravitreal injections: influence of the packaging device and storage conditions
J. Claves1, A. Freisz1, V. Sautou2, Ph. Chennell2
1 CHU Clermont-Ferrand, Pôle Pharmacie, F-63003 Clermont-Ferrand, France2 Université Clermont Auvergne, CHU Clermont Ferrand, Clermont Auvergne INP, CNRS, ICCF,
F-63000 Clermont-Ferrand, France
Stability indicating HPLC method development of Carbimazole tablets and stability study of the repackaged tablet
D. Malnoë, L. Regnier, A-L. Leroy, M.-A. Lester, P-N. BoivinCentre Hospitalier Universitaire de Rennes, Pôle Pharmacie, Secteur Pharmacotechnie et Onco-Pharmacie, 35033 Rennes, France
Preliminary validation results of an alternative sterility test for hospital injectable anticancer drugs
Y. Ghomari1,2, T. Martin2, P-H. François2, A. Bendjama2, P. Coliat21: Faculty of Pharmacy, University of Lille, FRANCE
2: Pharmacy Department, Institut de Cancérologie Strasbourg Europe - ICANS, Strasbourg, FRANCE
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Stability Study of a Buccal Hydrogel Containing 2% Lidocaine (20mg/g) and 0.05% Clobetasol (500µg/g) Used for the Treatment and Relief of Mucositis
C. Fresneau, C. Gazel, P. Claraz, C. Guillemot, F. PuissetHospital pharmacy, Institut Universitaire du Cancer Toulouse - Oncopole, France
Two-chamber bags: A New Packaging Solution for Unstable Injectable Anticancer Drug Preparations?
L. Nobilet1, L. Hassani1, M. Detroit1, N. Castor1, V. Multon1, D. Schlemmer2, M. Antignac1, D. Combeau1, A. Desnoyer1, H. Sadou Yaye11 Pharmacie, AP-HP Sorbonne Université Groupe Hospitalier Pitié Salpêtrière, Paris, France
2 Laboratoire de suivi thérapeutique pharmacologique spécialisé, AP-HP Sorbonne Université Groupe Hospitalier Pitié Salpêtrière, Paris, France
Development of a Stability-Indicating, Predictive, and Prospective Study of a Semi-Solid Formulation of Butylscopolamine Bromide (BBS)
- F. Louli1, M. Venet1, N. Blot-Barzic1, C. Marchand1, C. Merienne1, F. Pirot1,2
1 Hospices Civils de Lyon (HCL) - Unité de Préparation et de Contrôle des Médicaments, plateforme FRIPHARM, Pharmacie à usage intérieur, Groupement Hospitalier Edouard Herriot, Hospices Civils de Lyon, France
2 Université Claude Bernard Lyon-1, Faculté de Pharmacie de Lyon, Laboratoire de Biologie tissulaire et Ingénierie Thérapeutique UMR-CNRS 5305, France
To flip or not to flip : toward a change in pratices ?
L. Parrain, C. Lakhmi, J. Giraud, C. FournierHôpital Saint-Vincent de Paul, Lille, France
The QUOMET Project: Quantifying Shock Levels in Pharmaceutical Transport to Ensure Medication Safety
F. Marçon1,2, L. Dégrugilliers11 Centre Hospitalier Universitaire d’Amiens Picardie, Amiens, France
2 Université de Picardie Jules Verne, Laboratoire AGIR UR4294, Amiens, France
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Carbon footprint of a chemotherapy production unit: assessment within a hospital pharmacy
M. Chabane1, C. Fagnoni-Legat1, C. Hosotte2, M. Jehl-Rave1, G. Barbier1, S. Bonnot-Perrin1, L. Carrez2, S. Limat1,3, M. Kroemer1,31 CHU de Besançon, Pharmacie, Besançon, F-25000, France
2 Department of pharmacy, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
3 Université de Franche-Comté, EFS, INSERM UMR RIGHT, Besançon, F-25000, France
Strategy for controlling particulate contamination during renovation work while maintaining injectable drug production activity
D. Goulley1,2, M. Devaux1, C. Pernot11 Unité de Pharmacotechnie, CHU de Dijon, 14 rue Paul Gaffarel, 21000 Dijon, France
2 UFR Science de Santé, 9 Boulevard Jeanne d’Arc, 21000 Dijon, France
Optimizing automated chemotherapy preparation: determining the need for practice review
J. Duclos, P. Barreau, C. Tan, A. Villain, M. Abele, I. Sakji, G. MarliotCentre Oscar Lambret, Lille, France
HPuzzLC : enhancing HPLC proficiency in sterile compounding units by implementing a serious game-based training approach
F. Kerouredan1, M. Sangnier1, J-M. Bernadou1, A. Berroneau1, G. Bouguéon1,21 Unité de Pharmacotechnie, Centre Hospitalier Universitaire de Bordeaux, France
2 ARNA Laboratoire ChemBioPharm U1212 INSERM - UMR 5320 CNRS, Université de Bordeaux, France
A wall-mounted tubing transfer system: a solution to prevent chemical contamination !
C. Tan, L. Parrain, C. Lakhmi, J. Giraud, C. FournierService Pharmacie, Hôpital Saint-Vincent de Paul, Lille, France
Feedback from an error in the preparation of intrathecal analgesia
J-S. Giraud, E. Kobylarz, S. Busse, A. Acramel, A. Hurgon, R. Desmaris, C. CrosInstitut Curie, Paris, France
Panic in the cytotoxic drug production unit - Simulation of an Incident Exposing to Cytotoxic Contamination Risk
L. Pagnot, C. Buet, J. Palluaud, S. Etcheverry, E. DussossoyHospices Civils de Lyon, Groupement Hospitalier Nord, Hôpital de la Croix-Rousse, Pharmacie, Lyon, France
E-Posters - Session A :Quality Assurance, Risk Analysis and CSR
Performance Qualification of the robotic system APOTECAunit for non-toxic parenteral preparations
D. Ackermann, H. Linxweiler, J. Thiesen, I. Krämer
University Medical Center, Johannes Gutenberg-University, Langenbeckstraße 1, Mainz, Germany Pharmaceutical aseptic preparation on-call duty period: setting up a training and accreditation program for pharmacists G. Bouguéon, M. Sangnier, A. Berroneau
Bordeaux University Hospital, France Life Cycle Analysis of the Production of Three Hospital Preparations through an Advanced Pharmaco- Technical Eco-Audit M. Creyssel, C. Merienne, C. Marchand, F. Pirot
Hospices Civils de Lyon, France Focus on Continuous Training for On-Call Pharmacists : Tailored Resources and Personalized Training for Safe Validation and Manufacturing of Cytotoxic Products L. Zheng, A. Goubil, P. Chapron, E. Clapeau, C. Fronteau, N. Cormier
Centre Hospitalier Universitaire de Nantes, France Risk analysis of the non-sterile compounding activity and the impact of computerization in the preparation circuit C. Azam, C. Jurado, Z. Ramjaun
Centre Hospitalier Universitaire de Toulouse, France Quality review of sterile hospital preparations: a recommendation of Good Preparation Practices M. Bonnevay, B. Lapras, C. Merienne, C. Marchand, F. Pirot
Hospices Civils de Lyon, France Double-blind phase I-II clinical trials: preliminary risk analysis applied to the pharmaceutical circuit of injectable anticancer drugs in a preparation unit C. Galon, MT. Baylatry, AC. Joly, C. Fernandez, E. Seguin
AP-HP Sorbonne Université - Hôpital Saint-Antoine, Paris, France Double-blind phase I-II clinical trials: preliminary risk analysis applied to the pharmaceutical circuit of injectable anticancer drugs in a preparation unit C. Galon, MT. Baylatry, AC. Joly, C. Fernandez, E. Seguin
AP-HP Sorbonne Université - Hôpital Saint-Antoine, Paris, France Preparation of experimental injectable drugs: designing an e-learning tool to train tomorrow’s operators! L. Gasmi, J. Gabai, A. Gahbiche, F. Berrich, V. Bloch, A. Jacob, I. Belaid
AP-HP, Hôpital Lariboisière-Fernand Widal, Paris, France From the centralized cytotoxic reconstitution unit (CCRU) to the day care unit (DCU), all involved with chemical contamination: spread simulation L. Leyenberger, J. Pajot, M. Andanson Macchi, E. Sigward
Centre Hospitalier de Montluçon - Néris les Bains, France Risk Analysis on the Automated Syringe Filling Process Using the Smartfiller® Filling Machine S. Muhammad, B. Quitte, M. Jobard, M-L. Brandely-Piat, R. Batista
AP-HP Paris Cité University Center, Cochin Hospital, Paris (France) Performance Qualification of a Syringe Filling Machine, Smartfiller® S. Muhammad, B. Quitte, C. Ranza, M. Jobard, M-L. Brandely-Piat, R. Batista
APHP, Hôpital Cochin, Paris, France Evaluation audit of cytotoxic preparation isolator bio-cleaning practices according to 2022 Good Preparation Practices following positive bacteriological surface samples M. Murer, C. Ragazzon, A. Marchaud, E. Gravier, I. Grange
Centre Hospitalier Emile Roux, Le Puy-en-Velay, France
University Medical Center, Johannes Gutenberg-University, Langenbeckstraße 1, Mainz, Germany Pharmaceutical aseptic preparation on-call duty period: setting up a training and accreditation program for pharmacists G. Bouguéon, M. Sangnier, A. Berroneau
Bordeaux University Hospital, France Life Cycle Analysis of the Production of Three Hospital Preparations through an Advanced Pharmaco- Technical Eco-Audit M. Creyssel, C. Merienne, C. Marchand, F. Pirot
Hospices Civils de Lyon, France Focus on Continuous Training for On-Call Pharmacists : Tailored Resources and Personalized Training for Safe Validation and Manufacturing of Cytotoxic Products L. Zheng, A. Goubil, P. Chapron, E. Clapeau, C. Fronteau, N. Cormier
Centre Hospitalier Universitaire de Nantes, France Risk analysis of the non-sterile compounding activity and the impact of computerization in the preparation circuit C. Azam, C. Jurado, Z. Ramjaun
Centre Hospitalier Universitaire de Toulouse, France Quality review of sterile hospital preparations: a recommendation of Good Preparation Practices M. Bonnevay, B. Lapras, C. Merienne, C. Marchand, F. Pirot
Hospices Civils de Lyon, France Double-blind phase I-II clinical trials: preliminary risk analysis applied to the pharmaceutical circuit of injectable anticancer drugs in a preparation unit C. Galon, MT. Baylatry, AC. Joly, C. Fernandez, E. Seguin
AP-HP Sorbonne Université - Hôpital Saint-Antoine, Paris, France Double-blind phase I-II clinical trials: preliminary risk analysis applied to the pharmaceutical circuit of injectable anticancer drugs in a preparation unit C. Galon, MT. Baylatry, AC. Joly, C. Fernandez, E. Seguin
AP-HP Sorbonne Université - Hôpital Saint-Antoine, Paris, France Preparation of experimental injectable drugs: designing an e-learning tool to train tomorrow’s operators! L. Gasmi, J. Gabai, A. Gahbiche, F. Berrich, V. Bloch, A. Jacob, I. Belaid
AP-HP, Hôpital Lariboisière-Fernand Widal, Paris, France From the centralized cytotoxic reconstitution unit (CCRU) to the day care unit (DCU), all involved with chemical contamination: spread simulation L. Leyenberger, J. Pajot, M. Andanson Macchi, E. Sigward
Centre Hospitalier de Montluçon - Néris les Bains, France Risk Analysis on the Automated Syringe Filling Process Using the Smartfiller® Filling Machine S. Muhammad, B. Quitte, M. Jobard, M-L. Brandely-Piat, R. Batista
AP-HP Paris Cité University Center, Cochin Hospital, Paris (France) Performance Qualification of a Syringe Filling Machine, Smartfiller® S. Muhammad, B. Quitte, C. Ranza, M. Jobard, M-L. Brandely-Piat, R. Batista
APHP, Hôpital Cochin, Paris, France Evaluation audit of cytotoxic preparation isolator bio-cleaning practices according to 2022 Good Preparation Practices following positive bacteriological surface samples M. Murer, C. Ragazzon, A. Marchaud, E. Gravier, I. Grange
Centre Hospitalier Emile Roux, Le Puy-en-Velay, France
E-Posters - Session B: Feasibility studies - Formulations
Database creation on the feasibility of galenic modification of oral anticancer drugs
C. Gazel, C. Fresneau, P. Claraz, F. Puisset, C. Guillemot
Institut Universitaire du Cancer Toulouse - Oncopole, France Capability analysis of a powder for filling by an automatic hard capsule filler A. Melaye, N. Thomasset, M. Decuyper, L. Pacqueu, M. Vasseur, M. Bouchfaa, P. Odou
Centre Hospitalier Universitaire de Lille, France Effectiveness of Ultraviolet C Decontamination: Identifying Optimal Exposure Times for Reducing Common Hospital Bacterial Strains A. Tabbakh, A. Bardel, I. Fredenucci, A. Ehmke, P. Cassier, T. Briot
Hospices Civils de Lyon, France Evaluation of the Feasibility of Preparing Patches in Vaseline for the Toxidermia Eploration in Immuno-Allergology E. Aussourd, Z. Riffi, N. Poletto, S. Parat
Centre Hospitalier Lyon Sud, France Feasibility study of implementing flow cytometry in a fecal microbiota transplant preparation unit V. Baillieu, S. Delage, M-T. Baylatry, C. Fernandez, A-C. Joly, R. Sintes
APHP, Hôpital Saint-Antoine, Paris, France Comparison of the rheological behaviour of ready-to-use suspension vehicles and formulated for patients with swallowing disorders P. Claraz, L. Fillaudeau, C. Guillemot, F. Puisset, C. Arellano
IUCT Oncopole, Toulouse, France Development of an experimental drug and implementation of its preparation on automatic capsule fillers S. Meziani, C. Merienne, C. Marchand, C. Dhelens, F. Pirot
Hospices Civils de Lyon, France Magistral preparation of chloroquine phosphate capsules for the treatment of lupus patients: Example of an active principle with a narrow therapeutic range requiring manipulation under conditions G. Fossas, S. Naffat, M. Cristofoli, C. Merienne, C. Marchand, F. Pirot
Hospices Civils de Lyon, France Hospital preparation of sterile vaseline oil: a rapid response to a worldwide shortage M. Cristofoli, E. Gonnard-Desechaud, C. Marchand, C. Merienne, F. Pirot
Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon, France Drug shortage of oral corticosteroids: Development of a prednisone 5 mg capsule formulation adapted to an automated preparation process M. Decuyper, V. Hay, A. Melaye, L. Pacqueu, L. Negrier, C. Danel, M. Vasseur, M. Bouchfaa, P. Odou
Centre Hospitalier Universitaire de Lille, France Feasibility study: Semi-automated preparation and filling of continuous 5-fluorouracil (5-FU) administration devices V. Demen, H. Nonni, A. Lecoutre, J. Courtin, M. Vasseur, P. Odou
Centre Hospitalier Universitaire de Lille, France Feasibility Study of Bacterial Endotoxin Testing in Hospital Preparations of 10% Glycerol / 5% Fructose C. Gras Girard, P. Chapron, A. Goubil, E. Olivier, N. Cormier
Centre Hospitalier Universitaire de Nantes, France
Institut Universitaire du Cancer Toulouse - Oncopole, France Capability analysis of a powder for filling by an automatic hard capsule filler A. Melaye, N. Thomasset, M. Decuyper, L. Pacqueu, M. Vasseur, M. Bouchfaa, P. Odou
Centre Hospitalier Universitaire de Lille, France Effectiveness of Ultraviolet C Decontamination: Identifying Optimal Exposure Times for Reducing Common Hospital Bacterial Strains A. Tabbakh, A. Bardel, I. Fredenucci, A. Ehmke, P. Cassier, T. Briot
Hospices Civils de Lyon, France Evaluation of the Feasibility of Preparing Patches in Vaseline for the Toxidermia Eploration in Immuno-Allergology E. Aussourd, Z. Riffi, N. Poletto, S. Parat
Centre Hospitalier Lyon Sud, France Feasibility study of implementing flow cytometry in a fecal microbiota transplant preparation unit V. Baillieu, S. Delage, M-T. Baylatry, C. Fernandez, A-C. Joly, R. Sintes
APHP, Hôpital Saint-Antoine, Paris, France Comparison of the rheological behaviour of ready-to-use suspension vehicles and formulated for patients with swallowing disorders P. Claraz, L. Fillaudeau, C. Guillemot, F. Puisset, C. Arellano
IUCT Oncopole, Toulouse, France Development of an experimental drug and implementation of its preparation on automatic capsule fillers S. Meziani, C. Merienne, C. Marchand, C. Dhelens, F. Pirot
Hospices Civils de Lyon, France Magistral preparation of chloroquine phosphate capsules for the treatment of lupus patients: Example of an active principle with a narrow therapeutic range requiring manipulation under conditions G. Fossas, S. Naffat, M. Cristofoli, C. Merienne, C. Marchand, F. Pirot
Hospices Civils de Lyon, France Hospital preparation of sterile vaseline oil: a rapid response to a worldwide shortage M. Cristofoli, E. Gonnard-Desechaud, C. Marchand, C. Merienne, F. Pirot
Groupement Hospitalier Edouard Herriot - Hospices Civils de Lyon, France Drug shortage of oral corticosteroids: Development of a prednisone 5 mg capsule formulation adapted to an automated preparation process M. Decuyper, V. Hay, A. Melaye, L. Pacqueu, L. Negrier, C. Danel, M. Vasseur, M. Bouchfaa, P. Odou
Centre Hospitalier Universitaire de Lille, France Feasibility study: Semi-automated preparation and filling of continuous 5-fluorouracil (5-FU) administration devices V. Demen, H. Nonni, A. Lecoutre, J. Courtin, M. Vasseur, P. Odou
Centre Hospitalier Universitaire de Lille, France Feasibility Study of Bacterial Endotoxin Testing in Hospital Preparations of 10% Glycerol / 5% Fructose C. Gras Girard, P. Chapron, A. Goubil, E. Olivier, N. Cormier
Centre Hospitalier Universitaire de Nantes, France
E-Posters - Session C: Stability studies and quality control
Study of the microbiological stability and preservative efficiency of a 2 mg/mL hydrochlorothiazide oral suspension in Inorpha®
A. Arouba, S. Muhammad, H. Garrigue, T. Daniel, F. Bordet, M-L. Maestroni
Centre Hospitalier Sud Francilien, Corbeil Essonnes, France Drugcam®: How to qualify it? L. Caillier, S. Kalimouttou, E. Rémy
Centre Hospitalier intercommunal Elbeuf-Louviers, Saint-Aubin-les-Elbeuf, France Study of forced degradation, by HPLC-UV and electrophoresis, of a new synthetic therapeutic elastic protein formulated in isotonic saline solution G. Fossas, V. Lequeux, A. Berthier, J-P. Salvi, C. Marchand, C. Merienne, F. Pirot, R. Debret
Hospices Civils de Lyon et UMR5305 CNRS/UCBL, Lyon, France Quality control issues not detected by chemotherapy video monitoring system S. Saïdani, E. Lenglet, Y. Bouattour, M. Jouannet, P. Chennell
Centre Hospitalier Universitaire de Clermont-Ferrand, France Sterility assay by membrane filtration method: Suitability test for 0.1% EDTA eye drops C. Dréano, A. Bourges, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France Stability study of a Betaxolol Oral Suspension Hospital Preparation L. Dubois, J. Barreau, C. Curti, C. Castera-Ducros, P. Vanelle
APHP, Hôpital de la Conception, Marseille, France Stability study of 10 mg/mL cyclophosphamide solution E. Gaud, A-L. Leroy, L. Regnier, P-N. Boivin, M-A. Lester
Centre Hospitalier Universitaire de Rennes, France Awareness of errors undetectable by DrugCam®: Evaluation of recognition by operators M. Gognard, A. Cau, A. Abdaoui, Y. Mahboub
Centre Hospitalier de Saint-Quentin, France Development of a stability-indicating assay and study of the physico-chemical stability of Etoposide phosphate in a 0.9% sodium chloride solution C. Gons, L. Roquefeuil, R. Ratiney, C. Cotteret, A. Schweitzer-Chaput
APHP, Hôpital Universitaire Necker Enfants Malades, France Determining a use-by date (UBD) on repackaged administration doses A. Heinrichs, C. Hanze, I. Roland
CHU of Liège, Belgium Preparation of etoposide injection concentrated at 10 mg/mL: Interest and physicochemical stability study S. Jegaden, M. Boucida, D. Alloh, P. Claraz, J. Roupret-Serzec, T. Storme, F. Rioblanc
APHP, Hôpital Universitaire Robert-Debré, Paris, France Stability study of a standardized parenteral nutrition formulation for premature neonates L. Leyenberger, C. Merienne, T. Briot
Hospices Civils de Lyon, France Physicochemical Stability Of Diluted “Akynzeo®” Infusion Solutions In Prefilled 0.9% Sodium Chloride Infusion Bags Z. Mittmann, I. Krämer, J. Thiesen
University Medical Center, Johannes Gutenberg-University, Mainz, Germany Development of spironolactone oral suspension for pediatric use and chemicophysical stability study using capillary electrophoresis and HPLC S. Sow, C. Fanjeaux, R. Vazquez, M-N.Guerrault-Moro
Centre Hospitalier Intercommunal de Poissy, Saint-Germain-en-Laye, France
Centre Hospitalier Sud Francilien, Corbeil Essonnes, France Drugcam®: How to qualify it? L. Caillier, S. Kalimouttou, E. Rémy
Centre Hospitalier intercommunal Elbeuf-Louviers, Saint-Aubin-les-Elbeuf, France Study of forced degradation, by HPLC-UV and electrophoresis, of a new synthetic therapeutic elastic protein formulated in isotonic saline solution G. Fossas, V. Lequeux, A. Berthier, J-P. Salvi, C. Marchand, C. Merienne, F. Pirot, R. Debret
Hospices Civils de Lyon et UMR5305 CNRS/UCBL, Lyon, France Quality control issues not detected by chemotherapy video monitoring system S. Saïdani, E. Lenglet, Y. Bouattour, M. Jouannet, P. Chennell
Centre Hospitalier Universitaire de Clermont-Ferrand, France Sterility assay by membrane filtration method: Suitability test for 0.1% EDTA eye drops C. Dréano, A. Bourges, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France Stability study of a Betaxolol Oral Suspension Hospital Preparation L. Dubois, J. Barreau, C. Curti, C. Castera-Ducros, P. Vanelle
APHP, Hôpital de la Conception, Marseille, France Stability study of 10 mg/mL cyclophosphamide solution E. Gaud, A-L. Leroy, L. Regnier, P-N. Boivin, M-A. Lester
Centre Hospitalier Universitaire de Rennes, France Awareness of errors undetectable by DrugCam®: Evaluation of recognition by operators M. Gognard, A. Cau, A. Abdaoui, Y. Mahboub
Centre Hospitalier de Saint-Quentin, France Development of a stability-indicating assay and study of the physico-chemical stability of Etoposide phosphate in a 0.9% sodium chloride solution C. Gons, L. Roquefeuil, R. Ratiney, C. Cotteret, A. Schweitzer-Chaput
APHP, Hôpital Universitaire Necker Enfants Malades, France Determining a use-by date (UBD) on repackaged administration doses A. Heinrichs, C. Hanze, I. Roland
CHU of Liège, Belgium Preparation of etoposide injection concentrated at 10 mg/mL: Interest and physicochemical stability study S. Jegaden, M. Boucida, D. Alloh, P. Claraz, J. Roupret-Serzec, T. Storme, F. Rioblanc
APHP, Hôpital Universitaire Robert-Debré, Paris, France Stability study of a standardized parenteral nutrition formulation for premature neonates L. Leyenberger, C. Merienne, T. Briot
Hospices Civils de Lyon, France Physicochemical Stability Of Diluted “Akynzeo®” Infusion Solutions In Prefilled 0.9% Sodium Chloride Infusion Bags Z. Mittmann, I. Krämer, J. Thiesen
University Medical Center, Johannes Gutenberg-University, Mainz, Germany Development of spironolactone oral suspension for pediatric use and chemicophysical stability study using capillary electrophoresis and HPLC S. Sow, C. Fanjeaux, R. Vazquez, M-N.Guerrault-Moro
Centre Hospitalier Intercommunal de Poissy, Saint-Germain-en-Laye, France
E-Posters - Session D: Production, automation and microbiological control processes
Access to replay of these recorded presentations
Moderators : S Crauste-Manciet (Angers - France) - I Roland (Liège - Belgium)
Artificial intelligence management system : what impact on the availability time of chemotherapy ?
L. Parrain, C. Martelet, C. Genet, C. Lakhmi, J. Giraud, C. FournierHôpital Saint Vincent-de-Paul, Lille, France Near infrared spectroscopy – multivariate analysis: a proof-of-concept study for non-destructive quality control of pharmaceutical preparations M. Barrieu, J. Claves, M. Yessad, Y. Bouattour, M. Jouannet, Ph. Chennell
Université Clermont Auvergne et CHU Clermont-Ferrand, Clermont-Ferrand, France Efficiency of an optimized decontamination procedure for five intravenous antineoplastic drugs in a compounding isolator of a hospital pharmacy: a real-life study G. Hily, G. Bouguéon, A. Villa, A. Berroneau, M. Canal-Raffin
Centre Hospitalier Universitaire de Bordeaux, France Facing the threat of cyberattack: developing an activity continuity software for the production of anticancer drugs N. Loche, D. Giraud, E. Pinet, M. Dayre, E. Caudron, L. Lê
APHP, Hôpital Européen Georges-Pompidou, France Robotics and chemotherapy preparation: what impacts on staff quality of life and working conditions (QWLC)? S. Benkhoris, A. Goubil, P. Chapron, V. Laurent, C. Fronteau, E. Clapeau, N. Cormier
Centre Hospitalier Universitaire de Nantes, France Comparison between two types of water baths (wet and dry) in the context of the CAR-T cell reinjection circuit O. Bourgogne, G. Flandin, C. Cesbron, A. Grand, C. Spinau, C. Ruiz, R. Desquines, J-M. Canonge
IUCT Oncopole, Toulouse, France Contribution of dose harmonization to the reallocation of preparations M. Cabané-Chrestia, C. Born, J. Lecordier, S. Ruck, C. Thil-Kuntz, M. Auburtin, J-J. Lahet
Centre Hospitalier Emile Durkheim, Epinal, France Development of automated capsule production for hospital pharmacies M. Decuyper, V. Hay, A. Melaye, L. Pacqueu, M. Vasseur, M. Bouchfaa, P. Odou
Centre Hospitalier Universitaire de Lille, France Flow rate conservation test of Folfusor SV 2ml/h diffusers: towards an extension of expiry date? Z. Gachouch, C. Jouini, R. Meghnagi, P. Hercheux, N. Desrayaud, I. Madelaine-Chambrin, M. Brault
APHP, Hôpital Saint-Louis, Paris, France Exoskeleton or arm holder: which equipment to limit musculoskeletal disorders among our pharmacy technicians? C. Galon, C-L. Mansi-Makanda, V. Brigolle, M-T. Baylatry, E. Seguin, C. Fernandez, A-C. Joly, F. Yav
AP-HP Sorbonne Université - Hôpital Saint-Antoine, Paris, France Sterilization of neoprene gloves used to preparations shielded enclosure and microbiological assessment in radiopharmacy M. Debarge, A. Lombard, M. Sacrez, E. Loison, F. Benoit, Q. Citerne, N. Veran, B. Demore
Hospital pharmacy, CHRU Nancy, Vandoeuvre-lès-Nancy, France Trend Analysis of Microbiological Samples within Isolators C. Mondésir, A. Jouvance, M-A. Lester
Centre Hospitalier Universitaire de Rennes, France Mapping of the bacterial flora of products entering the Controlled Atmosphere Zone: catch them all! A. Srinivassan, A. Glavieux, C. Melin-Lafarge
Centre Hospitalier de Périgueux, France In the Depths of the Fecal Microbiota: Unveiling the Secrets of Its Production C. Stampfli, R. Sintes, M. Audry, A. Mitouassiwou-Samba, F. Aparicio, A. Ballif, T. Galperine, B. Guery, L. Carrez, F. Sadeghipour
Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse
E-Posters - Session E: Analytical techniques
The spectra of anthracyclines analyzed
A. Chettrit, L. Le Meur, L. Falconieri, M-S. Malin, M. Rigal, A. Jacolot, M. Apparuit
APHP, Hôpital Avicenne, Bobigny, France Validation of an assay method for lidocaine, prilocaine and tetracaine using UV detection high- performance liquid chromatography B. Farguet, A. Pinard, B. Do, M. Paul
Hôpital Henri-Mondor, Assistance Publique des Hôpitaux de Paris, France Validation of an assay method for lidocaine, prilocaine and tetracaine using UV detection high- performance liquid chromatography B. Farguet, A. Pinard, B. Do, M. Paul
Hôpital Henri-Mondor, Assistance Publique des Hôpitaux de Paris, France Development of a sampling method to validate the cleaning process of an automatic hard capsule filler V. Hay, M. Decuyper, L. Negrier, C. Danel, M. Roche, M. Vasseur, M. Bouchfaa, L. Pacqueu, P. Odou
Centre Hospitalier Universitaire de Lille, France Control of injectable preparations in a centralized preparation unit: identification of an assay interference between monoclonal antibodies and 5-Fluorouracil by UV/Raman spectrophotometry M. Nehlil, P. Legrand, M. Sangnier, J-M. Bernadou, A. Berroneau, G. Bouguéon
Bordeaux University Hospital, France Validation of an Assay Method for an Aqueous Solution of Trichloroacetic Acid: Benefits of Automated Acid-Base Titration L. Radou, C. Dréano, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France Impact of the analytical optimization of a cation quantification method by capillary electrophoresis using the RGB tool L. Palmier, L. Wnuk, M. Barrieu, L. Ben Salah, A. Buch, M. Mula, J. Claves, P. Chennell, Y. Bouattour, V. Sautou
Centre Hospitalier Universitaire de Clermont-Ferrand, France Flow injection analysis with UV detection versus Raman spectroscopy for the quantitative analysis of Remdesivir M. Berge, J. Siboni, C. Mequinion, E. Caudron, L. Lê
APHP, Hôpital Européen George-Pompidou, Paris et Université Paris Saclay, Orsay, France Development and validation of a method for the determination of Topiramate by high-performance liquid chromatography coupled to a charged aerosol detector (HPLC-CAD) M. Boucida, S. Jegaden, F. Rioblanc, J. Roupret-Serzec, T. Storme, D. Alloh
APHP, Hôpital Universitaire Robert-Debré, Paris, France Development and validation of a photometric titration method: Spotlighting! C. Dréano, S. Maisonneuve, A. Nicolas, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France The use of Raman spectroscopy in a hospital pharmacy setting Ellen Hagesaether, Randi Hamre Svendsen, Espen Gleditsch, Ingeborg Karboe, Serwornu (Theo) Dogbeten, Sarah Maud Fischer, Carl Niklas Nilsson
Oslo Hospital Pharmacy Rikshospitalet, Sognvannsveien 20, Norway Development of a «flash» method based on thin-layer-chromatography for radiochemical purity assessment of 99mTc-tetrofosmin L. Leyenberger, C. Grosjean, M. Andanson Macchi, C. Brentot
Centre Hospitalier de Montluçon - Néris les Bains, France
APHP, Hôpital Avicenne, Bobigny, France Validation of an assay method for lidocaine, prilocaine and tetracaine using UV detection high- performance liquid chromatography B. Farguet, A. Pinard, B. Do, M. Paul
Hôpital Henri-Mondor, Assistance Publique des Hôpitaux de Paris, France Validation of an assay method for lidocaine, prilocaine and tetracaine using UV detection high- performance liquid chromatography B. Farguet, A. Pinard, B. Do, M. Paul
Hôpital Henri-Mondor, Assistance Publique des Hôpitaux de Paris, France Development of a sampling method to validate the cleaning process of an automatic hard capsule filler V. Hay, M. Decuyper, L. Negrier, C. Danel, M. Roche, M. Vasseur, M. Bouchfaa, L. Pacqueu, P. Odou
Centre Hospitalier Universitaire de Lille, France Control of injectable preparations in a centralized preparation unit: identification of an assay interference between monoclonal antibodies and 5-Fluorouracil by UV/Raman spectrophotometry M. Nehlil, P. Legrand, M. Sangnier, J-M. Bernadou, A. Berroneau, G. Bouguéon
Bordeaux University Hospital, France Validation of an Assay Method for an Aqueous Solution of Trichloroacetic Acid: Benefits of Automated Acid-Base Titration L. Radou, C. Dréano, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France Impact of the analytical optimization of a cation quantification method by capillary electrophoresis using the RGB tool L. Palmier, L. Wnuk, M. Barrieu, L. Ben Salah, A. Buch, M. Mula, J. Claves, P. Chennell, Y. Bouattour, V. Sautou
Centre Hospitalier Universitaire de Clermont-Ferrand, France Flow injection analysis with UV detection versus Raman spectroscopy for the quantitative analysis of Remdesivir M. Berge, J. Siboni, C. Mequinion, E. Caudron, L. Lê
APHP, Hôpital Européen George-Pompidou, Paris et Université Paris Saclay, Orsay, France Development and validation of a method for the determination of Topiramate by high-performance liquid chromatography coupled to a charged aerosol detector (HPLC-CAD) M. Boucida, S. Jegaden, F. Rioblanc, J. Roupret-Serzec, T. Storme, D. Alloh
APHP, Hôpital Universitaire Robert-Debré, Paris, France Development and validation of a photometric titration method: Spotlighting! C. Dréano, S. Maisonneuve, A. Nicolas, V. Lebreton
Centre Hospitalier Universitaire d’Angers, France The use of Raman spectroscopy in a hospital pharmacy setting Ellen Hagesaether, Randi Hamre Svendsen, Espen Gleditsch, Ingeborg Karboe, Serwornu (Theo) Dogbeten, Sarah Maud Fischer, Carl Niklas Nilsson
Oslo Hospital Pharmacy Rikshospitalet, Sognvannsveien 20, Norway Development of a «flash» method based on thin-layer-chromatography for radiochemical purity assessment of 99mTc-tetrofosmin L. Leyenberger, C. Grosjean, M. Andanson Macchi, C. Brentot
Centre Hospitalier de Montluçon - Néris les Bains, France
